IN SILICO COMPARISON OF SEPARATE OR COMBINATORIAL EFFECTS OF PO-TENTIAL INHIBITORS OF THE SARS-COV-2 BINDING SITE OF ACE2

In Silico Comparison of Separate or Combinatorial Effects of Po-tential Inhibitors of the SARS-CoV-2 Binding Site of ACE2

Background: The COVID-19 is a pandemic viral infection with a high morbidity rate, leading to many worldwide deaths since the end of Vest Top 2019.The RBD (Receptor Binding Domain) of SARS-CoV-2 through its spike utilizes several host molecules to enter host cells.One of the most important ones is the angiotensin-converting enzyme 2 (ACE2), an enzy

read more

Identification of Helicobacter pylori virulence factors and assessment of their pathogenic potential and pathogenic activity in patients with gastrointestinal disorders

Helicobacter pylori (H.pylori) is found everywhere (approximately 50%) in people in the world, causing various types of gastrointestinal diseases ranging from mild inflammation, ulcers, and sometimes, stomach cancer.This pathogen carries a diverse set of genes encoding several virulence factors.In this research, we look forward to isolating bacteri

read more

Inhibition of Irvingia gabonensis seed extract (OB131) on adipogenesis as mediated via down regulation of the PPARgamma and Leptin genes and up-regulation of the adiponectin gene

Abstract Background Endeavors to manage obesity have been heavily reliant on controlling energy intake and expenditure equilibrium, but have failed to curtail the overweight and obesity epidemic.This dynamic equilibrium is more complex than originally postulated and is influenced by lifestyle, calorie and nutrient intake, reward cravings and satiat

read more